Human neutrophil degranulation during extracorporeal circulation
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چکیده
منابع مشابه
Human neutrophil degranulation during extracorporeal circulation.
Cardiopulmonary bypass, especially when prolonged, may result in hemostatic failure and pulmonary dysfunction, which has been attributed to changes in platelets and leukocytes, respectively. It has been well documented that contact of blood with synthetic surfaces causes platelet activation. In this report, we explore mechanisms of the activation of neutrophils during simulated in vitro extraco...
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Extracorporeal circulation (ECC) used during cardiac surgery causes activation of several inflammatory systems. These events are not fully understood but are responsible for complications during the immediate postoperative period. Neutrophil gelatinase-associated lipocalin (NGAL), a member of the expanding lipocalin family, has recently been described as an inflammatory protein. In this study, ...
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Introduction: Tracheal chondrosarcoma (TCS) is a rare malignancy, with only 19 cases described in the literature to date. Case presentation: Herein, we presented the third-largest TCS with such an airway compromise that neither orotracheal intubation nor jet ventilation or even tracheostomy was possible. So, extracorporeal circulation was needed to excise the tumor in a one-stage procedure. Th...
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BACKGROUND Neutrophil is a major focus in efforts to ameliorate the systemic inflammatory response associated with cardiopulmonary bypass. Neutrophil elastase is a powerful proteolytic enzyme, and plays a pivotal role in the development of the inflammatory response. This study assesses the inhibitory effects of sivelestat, a highly specific neutrophil elastase inhibitor, on elastase levels, cyt...
متن کاملStudies on cardiac lymph during extracorporeal circulation.
Cardiac lymph in dogs was used to study the metabolism and state of the myocardium during extracorporeal circulation and various additional procedures. Changes in the flow characteristics, cdor and pH of lymph were noted, and corresponding samples of cardiac lymph and coronary sinus blood were analyzed for lactate concenlmtion. Ventricular fibrillation led to higher lactate levek when compared ...
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ژورنال
عنوان ژورنال: Blood
سال: 1987
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v69.1.324.bloodjournal691324